Immunopharmacology

Mathison R, et al. Modulation of neutrophil function by the tripeptide feG. BMC Immunol. 2003 Mar 4;4:3. 2003

Mathison R, et al.  Regulation of leukocyte adhesion to heart by the tripeptides feG and feG(NH2). Can J Physiol Pharmacol. 2001 Sep; 79(9):785-92.

Mathison RD and Davison JS.  The Tripeptide feG Regulates the Production of Intracellular Reactive Oxygen Species by Neutrophils. J Inflamm (Lond). 2006 Jun 15;3(1):9

Mathison R, Davison JS, Befus AD. Neuroendocrine regulation of inflammation and tissue repair by submandibular gland factors. Immunol Today. 1994 Nov;15(11):527-32.

Mathison RD, et al. The tripeptide feG inhibits leukocyte adhesion. J Inflamm (Lond). 2008 May 20;5:6.

Mathison R, Davison JS. Molecular characteristics of the tripeptide feG accounting for different biological activities. Proc West Pharmacol Soc. 2007;50:101-4.

Mathison RD, et al.. A peptide from the submandibular glands modulates inflammatory responses.  Int Arch Allergy Immunol. 1997 May-Jul;113(1-3):337-8.

Mathison RD, et al.  Submandibular glands: novel structures participating in thermoregulatory responses.  Can J Physiol Pharmacol. 1997 May; 75(5):407-13.

Neurological Trauma

Bao F, et al. The tripeptide phenylalanine-(D) glutamate-(D) glycine modulates leukocyte infiltration and oxidative damage in rat injured spinal cord. Neuroscience. 2006 Jul 7;140(3):1011-22.

John SM, Bao F, Chen Y, Mathison RD, Weaver LC.Effects of a novel tripeptide on neurological outcomes after spinal cord injury. Neuroreport. 2006 Nov 27;17(17):1793-6.

Allergic/Anaphylaxis/IgE mediated

Dery RE, et al..  Frontline: Inhibition of allergen-induced pulmonary inflammation by the tripeptide feG: a mimetic of a neuro-endocrine pathway. Eur J Immunol. 2004 Dec;34(12):3315-25.

Turesin F, et al.: The tripeptide FEG ameliorates systemic inflammatory responses to rat intestinal anaphylaxis. BMC Physiol 2002, 2:13

Mathison RD, Davison JS, Befus AD. The tripeptide feG reduces perturbation of intestinal motility provoked by anaphylaxis. Proc West Pharmacol Soc. 2001;44:157-8.

Mathison R, et al. Attenuation of intestinal and cardiovascular anaphylaxis by the salivary gland tripeptide FEG and its D-isomeric analog feG. Peptides. 1998;19(6):1037-42.

Dery RE, Mathison R, Davison J, Befus AD.  Inhibition of allergic inflammation by C-terminal peptides of the prohormone submandibular rat 1 (SMR-1). Int Arch Allergy Immunol. 2001 an-Mar;124(1-3):201-4.

Endotoxin/Sepsis

Tan D, et al.  The carboxamide feG(NH2) inhibits endotoxin perturbation of intestinal motility. Eur J Pharmacol. 2000 Dec 8;409(2):203-5.

Mathison R, et al. The tripeptide feG reduces endotoxin-provoked perturbation of intestinal motility and inflammation. Neurogastroentero Motil. 2001 Dec;13(6):599-603.

Pancreatitis

Rifai Y, et al. The tripeptide analog feG ameliorates severity of acute pancreatitis in a caerulein mouse model.  Am J Physiol Gastrointest Liver Physiol.2008 Apr;294(4):G1094-9.